Myoglobin, Creatine-Kinase-MB and Cardiac Troponin-I 60-Minute Ratios Predict Infarct-related Artery Patency After Thrombolysis for Acute Myocardial Infarction
نویسنده
چکیده
RESULTS Angiography at 60 min showed a patent IRA (TIMI flow grade 2, 3) in 344 and occluded IRA (TIMI flow grade 0, 1) in 98 patients. The median serum T60 concentration, the ratio of the T60 and T0 serum concentration (60-min ratio) and the slope of increase over 60 min for each serum marker were significantly higher in patients with patent arteries compared with patients with occluded arteries. The area under the receiver-operating characteristic (ROC) curve for diagnosis of occlusion was 0.71, 0.70 and 0.71 for the 60-min ratio of myoglobin, cTnI and CKMB, respectively. The 60-min ratios of $4.0 for myoglobin, $3.3 for CK-MB and $2.0 for cTnI yielded a probability of patency of 90%, 88% and 87%, respectively.
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